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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM620027'
TargetCoagulation factor XI(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM620027((3S,8aS)-3-(5-(6-Amino-2-chloropyridin-3-yl)-1H-im...)
Affinity DataIC50:  0.300nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent