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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Collagenase 3' and Ligand = 'BDBM50239950'
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed