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Found 2 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM29442'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM29442(CHEMBL524616 | Pyrazolo[1,5-a]-1,3,5-triazine, 12-...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

LigandPNGBDBM29442(CHEMBL524616 | Pyrazolo[1,5-a]-1,3,5-triazine, 12-...)
Affinity DataIC50:  9.70nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed