Found 3 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50153477'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Salk Institute
Curated by ChEMBL
Salk Institute
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Displacement of [125ITyr0-Glu1,Nle17]-PS-Svg in human CRF-R1 expressed in COS-M6 cells after 90 mins by gamma counting assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Salk Institute
Curated by ChEMBL
Salk Institute
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Displacement of [125ITyr0-Glu1]-PD-Svg in human CRF-R1 expressed in COS-M6 cells after 90 mins by gamma counting assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.450nMAssay Description:Antagonist activity at CRF-R1 in mouse AtT-20 cells assessed as inhibition of human CRF induced cAMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair