Report error Found 9 Enz. Inhib. hit(s) with Target = 'Cyclin-G-associated kinase' and Ligand = 'BDBM50524284'
Affinity DataKi: 3.10nMAssay Description:Binding affinity to C-terminal AVI-tagged GAK (unknown origin) (12 to 347 residues) expressed in Escherichia coli after 1.5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of NanoBRET tracer 5 binding to NL-fused GAK (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of tracer 5 binding to human N-terminal nano luciferase-fused GAK expressed in HEK293 cells measured after 2 hrs by nanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of fluorescent tracer from N-terminus of human GAK expressed in HEK293T cells after 2 hrs by NanoBRET target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of GAK (unknown origin) by in-cell pulse based assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:Binding affinity to biotinylated human GAK (13 to 338 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent T...More data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Binding affinity to GAK (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to GAK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human wild type partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by KinomeScan methodMore data for this Ligand-Target Pair