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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1' and Ligand = 'BDBM6745'
Target
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human))
Eli Lilly
Ligand
BDBM6745
(1,7-Annulated indolocarbazole deriv. 13Ab | 7-fluo...)
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Affinity Data
IC50: 2nM
pH: 7.0 T: 2°C
Assay Description:
In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....
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