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Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 5 activator 1' and Ligand = 'BDBM601949'
Target
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human))
G1 Therapeutics
US Patent
Ligand
BDBM601949
(2'-((4-((4-methylpiperazin-1- yl)sulfonyl)phenyl)a...)
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Affinity Data
IC50: 7nM
Assay Description:
Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....
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Ligand Info
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US Patent
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