Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 1A2' and Ligand = 'BDBM50451549'
TargetCytochrome P450 1A2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50451549(CHEMBL4207737)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 15 mins in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50451549(CHEMBL4207737)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of CYP1A2 in human hepatocyte using phenacetin as substrate preincubated for 5 days followed by substrate addition and measured after 1 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed