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Found 2 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A' and Ligand = 'BDBM50330327'
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330327((R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cy...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330327((R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cy...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed