Found 2 Enz. Inhib. hit(s) with Target = 'DNA-(apurinic or apyrimidinic site) endonuclease' and Ligand = 'BDBM50066721'
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy of Sciences
Curated by ChEMBL
Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of full length human APE1 expressed in Escherichia coli BL21/DE3 assessed as inhibition of incision of depurinated supercoiled pUC18 plasm...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy of Sciences
Curated by ChEMBL
Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Binding affinity to full length human APE1 expressed in Escherichia coli BL21/DE3More data for this Ligand-Target Pair