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Found
1
Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM486410'
Target
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM486410
(N-(1,1-dioxidotetrahydrothiophen- 3-yl)-3-(2-fluor...)
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Affinity Data
IC50: 26nM
Assay Description:
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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