Report error Found 8 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM210929'
Affinity DataKi: 1.80nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of TMP/methicillin-resistant Staphylococcus aureus wild type DHFR assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihy...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dih...More data for this Ligand-Target Pair
Affinity DataKi: 389nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in NADPH oxidation using dihydrofolate as substrate preincubated for 5 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:IC50 values were determined following a standard method that has been described previously (Reeve et al., 2014, 2016).More data for this Ligand-Target Pair