Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50031872'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  280nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  280nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  430nMAssay Description:Inhibition of rat liver DHFR assessed as reduction in consumption of NADPH using DHFA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  430nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration inhibiting P. carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Saccharomyces cerevisiae)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031872(6-((2,5-dimethoxyphenylamino)methyl)pyrido[3,2-d]p...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed