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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50262653'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed