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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50448738'
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50448738(CHEMBL3127909)
Affinity DataKi:  0.0240nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50448738(CHEMBL3127909)
Affinity DataKi:  610nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed