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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50236630'
LigandPNGBDBM50236630(CHEMBL4076142)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236630(CHEMBL4076142)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236630(CHEMBL4076142)
Affinity DataIC50:  19nMAssay Description:Binding affinity for Protein kinase C delta C1b domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236630(CHEMBL4076142)
Affinity DataIC50:  20nMAssay Description:Inhibition of TACE in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed