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Found 2 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 8' and Ligand = 'BDBM50421690'
LigandPNGBDBM50421690(CHEMBL5276957)
Affinity DataIC50:  567nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
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LigandPNGBDBM50421690(CHEMBL5276957)
Affinity DataIC50:  800nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair
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