Found 2 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 8' and Ligand = 'BDBM50421690'
Affinity DataIC50: 567nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair