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Found 6 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50589392'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataIC50:  27nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human DYRK1AMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DYRK1AMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Escherichia coli using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589392(Adavivint | LORECIVIVINT | Lorecivivint | SM-04690...)
Affinity DataKd:  20nMAssay Description:Binding affinity to human DYRK1A assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed