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Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [124-240]' and Ligand = 'BDBM237579'
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237579(US9394263, 1a' | US9394263, 1b')
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237579(US9394263, 1a' | US9394263, 1b')
Affinity DataIC50:  267nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent