Report error Found 18 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50061101'
Affinity DataKi: 6.5nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Ability of the compound to displace endothelin ([125I]-ET-1) from human Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human endothelin A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to human ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Displacement of [I125]ET1 from recombinant ETA receptor expressed in CHO cells after 2 hrs by TopCount analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Displacement of 125I-ET1 from human smooth muscle ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Displacement of 125I-ET1 from human smooth muscle ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at ET-A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of radioligand from ETA receptor (unknown origin) expressed in fall armyworm sf9 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of radioligand from ETA receptor (unknown origin) expressed in fall armyworm sf9 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Binding affinity to recombinant human ETAMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Antagonist activity at ETA receptor (unknown origin) assessed as increase in G protein-mediated vasoconstrictionMore data for this Ligand-Target Pair
