Report error Found 2 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI' and Ligand = 'BDBM275886'
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataKi: 29.6nM ΔG°: -43.0kJ/molepH: 7.5 T: 25°CAssay Description:10 μM saFabI, 15 μM inhibitor, and 500 μM NADPH were preincubated overnight at room temperature followed by a 1:200 dilution into reac...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataKi: 110nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20° C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair