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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50147001'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50147001(CHEMBL3763405)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human EGFR L858R/T790M double mutant assessed as reduction in autophosphorylation of cytoplasmic domain by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50147001(CHEMBL3763405)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of wild type recombinant human EGFR assessed as reduction in autophosphorylation of cytoplasmic domain by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed