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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50494218'
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494218(CHEMBL3086102)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494218(CHEMBL3086102)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR L851Q mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494218(CHEMBL3086102)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) after 1.5 hrs by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494218(CHEMBL3086102)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494218(CHEMBL3086102)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed