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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50613692'
TargetEpidermal growth factor receptor(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50613692(CHEMBL5277269)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50613692(CHEMBL5277269)
Affinity DataKi:  18nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetEpidermal growth factor receptor(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50613692(CHEMBL5277269)
Affinity DataKi:  38nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50613692(CHEMBL5277269)
Affinity DataKi:  126nMAssay Description:Inhibition of human EGFR L858R mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50613692(CHEMBL5277269)
Affinity DataKi:  324nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed