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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M,L858R]' and Ligand = 'BDBM528566'
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM528566(US11896597, Compound 12 | US11896597, Compound 37)
Affinity DataIC50:  0.300nMAssay Description:The inhibition activity and the selectivity of the compounds against mutant EGFR and WT EGFR were assessed by using WT EGFR cell line A-431 (American...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM528566(US11896597, Compound 12 | US11896597, Compound 37)
Affinity DataIC50:  0.5nMAssay Description:The inhibition activity and the selectivity of the compounds against mutant EGFR and WT EGFR were assessed by using WT EGFR cell line A-431 (American...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent