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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM263919'
TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandPNGBDBM263919(US9714221, Example 215)
Affinity DataIC50:  31nMpH: 7.4 T: 25°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEstrogen receptor(Human)
Sanofi

US Patent
LigandPNGBDBM263919(US9714221, Example 215)
Affinity DataEC50:  1.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed