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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen receptor [Y537S]' and Ligand = 'BDBM443435'
TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3 | US10654866, Example 3A | U...)
Affinity DataKi:  6.69nMAssay Description:Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3 | US10654866, Example 3A | U...)
Affinity DataKi:  6.69nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3 | US10654866, Example 3A | U...)
Affinity DataKi:  6.69nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetEstrogen receptor [Y537S](Human)
Eli Lilly

US Patent
LigandPNGBDBM443435(US10654866, Example 3 | US10654866, Example 3A | U...)
Affinity DataKi:  27.2nMAssay Description:Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent