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Found 6 Enz. Inhib. hit(s) with Target = 'Estrogen receptor beta' and Ligand = 'BDBM50154057'
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataIC50:  49nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154057(2-(4-Hydroxy-phenyl)-benzooxazol-5-ol | 2-(4-hydro...)
Affinity DataEC50:  47nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed