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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM50525933'
TargetFibroblast growth factor receptor 3(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50525933(CHEMBL4568760)
Affinity DataIC50:  0.265nMAssay Description:Inhibition of human FGFR3 V555M mutant using FL-peptide substrate measured after 45 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50525933(CHEMBL4568760)
Affinity DataIC50:  0.971nMAssay Description:Inhibition of human FGFR3 wild-type using FL-peptide substrate measured after 50 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50525933(CHEMBL4568760)
Affinity DataIC50:  14nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) expressed in mouse NIH/3T3 cells overexpressing FGFR3-V555M mutant TACC3 assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50525933(CHEMBL4568760)
Affinity DataIC50:  17nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) expressed in mouse NIH/3T3 cells overexpressing wild type FGFR3-TACC3 assessed as inhibition of cell p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed