Report error Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50586343'
Affinity DataIC50: <10nMAssay Description:Inhibition of KRAS G12C mutant (2 to 188 residues) (unknown origin) expressed in Escherichia coli assessed as inhibition of SOS mediated nucleotide e...More data for this Ligand-Target Pair
Affinity DataEC50: <6.10nMAssay Description:Inhibition of KRAS G12C mutant in human HCC1171 cells assessed as effect on cell alkylation measured after 18 hrs by western blot analysisMore data for this Ligand-Target Pair