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Report error Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas [1-169,G12C,C118A]' and Ligand = 'BDBM544263'
TargetGTPase KRas [1-169,G12C,C118A](Human)
Amgen

US Patent
LigandPNGBDBM544263(US11285156, Ex.# 125-1)
Affinity DataIC50:  28nMAssay Description:Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent