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Report error Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas [G12D]' and Ligand = 'BDBM591397'
TargetGTPase KRas [G12D](Human)
Revolution Medicines

US Patent
LigandPNGBDBM591397(Synthesis of two atropisomers of (2S)-N-[(8S,14S,2...)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGTPase KRas [G12D](Human)
Revolution Medicines

US Patent
LigandPNGBDBM591397(Synthesis of two atropisomers of (2S)-N-[(8S,14S,2...)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent