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Report error Found 1 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E]' and Ligand = 'BDBM33253'
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2)
Novartis Institute For Tropical Diseases

LigandPNGBDBM33253(phthalazine-based compound, 4)
Affinity DataIC50:  2.74E+4nM Kd:  2.29E+4nMpH: 7.5 T: 37°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed