Found 4 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase' and Ligand = 'BDBM25308'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry
Curated by ChEMBL
Institute Of Biological Chemistry
Curated by ChEMBL
Affinity DataIC50: 1.07E+5nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair