Affinity DataIC50: 1.90nM EC50: 14.4nMpH: 7.5 T: 2°CAssay Description:The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasoneMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with CCL2-promoter luciferase plasmid construct assessed as reducti...More data for this Ligand-Target Pair
Affinity DataEC50: 521nMAssay Description:Inhibition of GR-mediated tyrosine amino transferase activity in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
Affinity DataEC50: 14.4nMAssay Description:GR-mediated transrepression of IL-6 in human A549 lung carcinoma cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair