Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM416667'
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM416667((2R)-2-Methoxy-2-[3-methoxy-5-(trifluoromethoxy)ph...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human KGA (63 to 669 residues) preincubated for 15 mins using 50 mM glutamine as substrate by resorufin dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM416667((2R)-2-Methoxy-2-[3-methoxy-5-(trifluoromethoxy)ph...)
Affinity DataIC50:  6.11nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent