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Found 2 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM173197'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173197(US10137122, Compound 53 | US9096594, 54)
Affinity DataIC50:  12nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173197(US10137122, Compound 53 | US9096594, 54)
Affinity DataIC50:  1.08E+6nMAssay Description:20 μL/well of 4.7 nM GSK3β and 7 μM peptide in KBA (250 mM HEPES (pH 7.5), 50 mM MgCl2, 5 mM EGTA, 0.05% BRIJ-35) were dispensed onto ...More data for this Ligand-Target Pair
In DepthDetails US Patent