Found 5 Enz. Inhib. hit(s) with Target = 'Glycylpeptide N-tetradecanoyltransferase 1' and Ligand = 'BDBM50148269' TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of human NMT1 R295Q/W297F/A452M/L453V/L462V/N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as subst...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to human N-myristoyltransferase by fluorescence analysisMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of human NMT1 L495M mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins b...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of human NMT1 N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA aft...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) expressed in Escherichia coli Rosetta-2 cells using GSN...More data for this Ligand-Target Pair
