Report error Found 9 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50533858'
Affinity DataIC50: 0.440nMAssay Description:Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Antagonist activity against human GnRH receptor expressed in human Chem1 cells assessed as inhibition of LHRH-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity against human GnRH receptor expressed in HEK293 cells assessed as reduction in ERK1/2 phosphorylation pre-incubated for 5 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 20...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity against monkey GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1...More data for this Ligand-Target Pair
Affinity DataIC50: 279nMAssay Description:Antagonist activity against rat GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Displacement of [125I]D-Trp6-LHRH from rat GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
