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Found
1
Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1' and Ligand = 'BDBM280968'
Target
Guanylate cyclase soluble subunit alpha-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM280968
(5-[4-(2H-tetrazol- 5-yl)pyridin-2- yl]-4-amino-2- ...)
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Affinity Data
Ki: 0.0620nM
pH: 7.4
Assay Description:
The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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