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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1' and Ligand = 'BDBM280973'
Target
Guanylate cyclase soluble subunit alpha-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM280973
(4-Amino-2-[1-(2-fluorobenzyl)-1H-indazol-3-yl]-5-m...)
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Affinity Data
Ki: 0.0480nM
pH: 7.4
Assay Description:
The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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