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Found 5 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50008059'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  16nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  70nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  70nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50:  200nMAssay Description:Inhibition of steady-state expression of Raf-1 in MCF-7 breast cancer cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to Heat Shock Protein 90 (unknown origin)More data for this Ligand-Target Pair