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Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50486034'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486034(CHEMBL2204501)
Affinity DataIC50:  21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486034(CHEMBL2204501)
Affinity DataIC50:  252nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed