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Found 4 Enz. Inhib. hit(s) with Target = 'Heme oxygenase 2' and Ligand = 'BDBM84804'
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University of Catania

Curated by ChEMBL
LigandPNGBDBM84804(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University of Catania

Curated by ChEMBL
LigandPNGBDBM84804(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Affinity DataIC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:Heme oxygenase activity in rat spleen and brain microsomal fractions was determined by the quantitation of CO formed from the degradation of methemal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University of Catania

Curated by ChEMBL
LigandPNGBDBM84804(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University of Catania

Curated by ChEMBL
LigandPNGBDBM84804(1-azolyl-4-phenyl-2-butanone, 6a | CHEMBL536514)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed