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Found
1
Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM376090'
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM376090
(5-(2-fluoro-5-(pyrimidin-2-yl)- 4- (trifluoromethy...)
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Affinity Data
IC50: 7nM
Assay Description:
In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...
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Target Info
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Ligand Info
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