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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 4' and Ligand = 'BDBM162839'
TargetHistone deacetylase 4(Homo sapiens (Human))
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM162839(US9056843, 130)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM162839(US9056843, 130)
Affinity DataIC50:  11nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Charles River Discovery

Curated by ChEMBL
LigandPNGBDBM162839(US9056843, 130)
Affinity DataIC50:  70nMAssay Description:Inhibition of Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed