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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM593406'
TargetHistone deacetylase 6(Homo sapiens (Human))
Tenaya Therapeutics

US Patent
LigandPNGBDBM593406(N-(6-cyanopyridin-3-yl-N-((5-(5- (difluoromethyl)...)
Affinity DataIC50:  10nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Tenaya Therapeutics

US Patent
LigandPNGBDBM593406(N-(6-cyanopyridin-3-yl-N-((5-(5- (difluoromethyl)...)
Affinity DataIC50:  10nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent