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Report error Found 11 Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM27879'
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMpH: 7.0 T: 30°CAssay Description:The IGF-1 receptor tyrosine kinase was assayed using the synthetic polymer poly(Glu/Tyr) as a phosphoacceptor substrate. Incorporated radioactivity w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory concentration against IGF-1R kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant IGF-1R tyrosine kinase expressed in baculovirus system assessed as [33gamma]ATP phosphorylation of poly(Glu/Tyr) subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IGF1R in mouse SAL cells assessed as thymidine incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory concentration against IGF-1R Sal kinase with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  153nMAssay Description:Inhibition of NH2-terminal glutathione S-transferase fused human recombinant IGF-IR catalytic domain expressed in insect cells using poly(Glu:Tyr) su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed