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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-4/beta-1' and Ligand = 'BDBM50106082'
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106082((S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-urei...)
Affinity DataIC50:  12nMAssay Description:In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106082((S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-urei...)
Affinity DataIC50:  14nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106082((S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-urei...)
Affinity DataIC50:  22nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50106082((S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-urei...)
Affinity DataIC50:  25nMAssay Description:Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed