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Report error Found 1 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP], mitochondrial [40-452,R172K]' and Ligand = 'BDBM50503278'
TargetIsocitrate dehydrogenase [NADP], mitochondrial [40-452,R172K](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50503278(CHEMBL4456102 | US10745383, Example 3)
Affinity DataIC50:  31.7nMAssay Description:The inhibitory activity of a compound against IDH2 (R172K, 40-end) was determined by the decrease of a helper factor NADPH. The test compound was pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent